Synthesis, Spectroscopic and Anti-microbial studies of Binuclear Schiff Base Complexes derived from the Ligand prepared from Isoniazid and Benzilmonohydrazone

The binuclear Schiff base complexes have been prepared newly using different transition metals at their stable oxidation states as Cu(II), Ni(II), and Co(II) with the ligand (L) obtained by the condensation of isoniazid and benzilmonohydrazone. The composition and structure of the complexes have been established by analytical and spectral data, thermal analysis, magnetic and conductivity measurements. The metalloligands as well as the macrocyclic complexes are found to have good antimicrobial activities against the pathogenic fungus Aspergillus niger, Helminthosporium oryzae and Fusarium oxysporium .The binuclear metal complexes were found to possess potent antimicrobial, antifungal activity better than the ligand.